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Huige Zhou

Visiting Scholar

Research interest

Nanodrug delivery system & Tumor imaging

Work Experience

2018.07 – 2024.02 Assistant Researcher, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing, China

2024.03 - present Associate Researcher, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing, China

Liang Zhao_edited_edited.jpg

E-mail: zhouhg@nanoctr.cn

Education Background

Ph.D., Nanoscience and Technology, National Center for Nanoscience and Technology, Chinese Academy of Sciences, 2018

B.Sc., Material Science and Engineering, Henan Polytechnic University, 2013

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Publication

  1. Zhou Xuantong#; Gao Fene#; Gao Wenyan; Wang Qingzhen; Li Xin; Li Xinyue; Li Wenxin; Liu Jing; Zhou Huige*; Luo Aiping*; Chen Chunying*; Liu Zhihua*, Bismuth Sulfide Nanoflowers Facilitated miR339 Delivery to Overcome Stemness and Radioresistance through Ubiquitin-Specific Peptidase 8 in Esophageal Cancer. ACS Nano 2024, 18, 19802.

  2. Zhou Huige#; Guo Yuecong#; Fu tianyu; Peng Yufeng; Chen Ziwei; Cui Yanyan; Guo Mengyu; Zhang Kai*; Chen Chunying*; Wang Yaling*, Three-Dimensional Label-Free Observing of the Self-Assembled Nanoparticles inside a Single Cell at Nanoscale Resolution. ACS Nano 2024, 18, 19232.

  3. Liu Tao#; Ma Manman#; Ali Arbab#; Liu Qiaolin; Bai Ru; Wang Qingzhen; Peng Yufeng; Zhang Kai; Guan Yong; Wang Yaling*; Liu Jing*; and Zhou Huige*, Self-assembled Copper Tannic Acid Nanoparticles: A Powerful Nano- Bactericide by Valence Shift of Copper. Nano Today 2024, 54, 102071.

  4. Zhang Xu#; Shi Kejian#; Wang Qingzhen; Zhang Jiakun; Bai Ru; Gao Fene; Liu Shihui; Guo Mengyu; Qin Fenglan; Li Shengmin; Chen Chunying; Zhou Huige*; Jing Liu*; Chen Fulin*, Ultra-strong Penetrating and GSH-responsive Oral Drug Delivery System Improved Therapeutic Effect of Gemcitabine for Pancreatic Tumor. Nano Today 2024, 54, 102048.  

  5. Liu Qiaolin; Zhao Yuliang; Zhou Huige*; Chen Chunying*, Ferroptosis: Challenges and Opportunities for Nanomaterials in Cancer Therapy. Regenerative Biomaterials 2023, 10, rbad004.

  6. Zhou Huige#; Guo Mengyu#; Li Jiayang#; Qin Fenglan; Wang Yuqing; Liu Tao; Liu Jing; Zeinab Farhadi Sabet; Wang Yaling; Liu Ying; Huo Qing; Chen Chunying*, Hypoxia-Triggered Self-Assembly of Ultra-Small Iron Oxide Nanoparticles to Amplify the Imaging Signal of a Tumor. Journal of the American Chemical Society 2021, 143, 1846.

  7. Zhou, Huige#; Qin, Fenglan#; Chen, Chunying*, Designing Hypoxia-Responsive Nano theranostic Agents for Tumor Imaging and Therapy. Advanced Healthcare Materials 2021, 10, 2001277.

  8. Arbab Ali#; Muhammad Ovais#; Zhou Huige#; Rui Yukui*; Chen Chunying*, Tailoring Metal-organic Frameworks-based Nanozymes for Bacterial Theranostics. Biomaterials 2021, 275, 120951.

  9. Gao Jinling#; Zhou, Huige#; Zhao, Yanjie; Lu, Lin; Zhang, Jianzhong; Cheng, Wenting; Song, Xuxia; Zheng, Yuxin; Chen, Chunying*; Tang, Jinglong*, Time-course Effect of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles on Intracellular Iron Metabolism and Ferroptosis Activation. Nanotoxicology 2021, 15, 366-379.

  10. Tang, Jianqin#; Zhou, Huige#; Hou, Xiaoyang; Wang, Liming; Li, Yaxi; Pang, Yanyu; Chen, Chunying*; Jiang, Guan*; Liu, Yanqun, Enhanced anti-Tumor Efficacy of Temozolomide-Loaded Carboxylated Poly(Amido-Amine) Combined with Photothermal/Photodynamic Therapy for Melanoma Treatment. Cancer Letters 2018, 423, 16.

  11. Zhou, Huige#; Tang, Jinglong#; Li, Jiayang; Li, Wanqi; Liu, Ying; Chen, Chunying*, In Vivo Aggregation-Induced Transition between T-1 and T-2 Relaxations of Magnetic Ultra-Small Iron Oxide Nanoparticles in Tumor Microenvironment. Nanoscale 2017, 9, 3040.

  12. Tang, Jinglong#; Zhou, Huige#; Liu, Jiaming; Liu, Jing; Li, Wanqi; Wang, Yuqing; Hu, Fan; Huo, Qing; Li, Jiayang; Liu, Ying; Chen, Chunying*, Dual-Mode Imaging-Guided Synergistic Chemo- and Magnetohyperthermia Therapy in a Versatile Nanoplatform to Eliminate Cancer Stem Cells. ACS Applied Materials & Interfaces 2017, 9, 23497.

  13. Zhou, Huige; Hou, Xiaoyang; Liu, Ying; Zhao, Tianming; Shang, Qiuyu; Tang, Jinglong; Liu, Jing; Wang, Yuqing; Wu, Qiuchi; Luo, Zehao; Wang, Hui; Chen, Chunying*, Superstable Magnetic Nanoparticles in Conjugation with near-Infrared Dye as a Multimodal Theranostic Platform. ACS Applied Materials & Interfaces 2016, 8, 4424.

  14. Hu, Kelei#; Zhou, Huige#; Liu, Ying*; Liu, Zhu; Liu, Jing; Tang, Jinglong; Li, Jiayang; Zhang, Jiakun; Sheng, Wang; Zhao, Yuliang; Wu, Yan*; Chen, Chunying*, Hyaluronic Acid Functional Amphipathic and Redox-Responsive Polymer Particles for the co-Delivery of Doxorubicin and Cyclopamine to Eradicate Breast Cancer Cells and Cancer Stem Cells. Nanoscale 2015, 7, 8607.


Research Grants:

  1. “Multi-mode Imaging of Tumor Associated Macrophages by Hypoxia-triggered Self-assembling and CD206 Targeting Ultra-small Iron Oxide Nanoparticles” (32000983), supported by National Natural Science Foundation of China, Principal Investigator.

  2. “Multistage Targeted Lipid Loading MCL1 Inhibitor S63845 Improves Platinum Resistance of Ovarian Cancer” (H1815/82272726), supported by National Natural Science Foundation of China, Co-Principal Investigator.

  3. “Designing Smart Nano-Drug to Enhance Their Accumulation in Tumor Tissues and Regulate Tumor Microenvironment” (ZDBS-LY-SLH039), supported by Chinese Academic of Sciences, Co-Principal Investigator.

  4.   “In Vivo Construction of Polypeptide Nanostructures and Their Application in the Diagnosis and Treatment of Urinary Tumors” (SQ2022YFA1200063), supported by National Key R&D Program of China, Sub-Principal Investigator.


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