Guangyao Zhang
Visiting scholar
Research interest
Metal–Organic Framework Nanozymes for Sensing and Biomedical Applications
Work Experience
2019-Present Associate Prof., College of Textiles&Clothing, Qingdao University
Education Background
Ph.D., Chemical Engineering & Technology, Nanjing University of Science & Technology, 2017
B.Sc., Bioengineering, Wuhan University of Bioengineering, 2012
E-mail: dnrv57@visitor.nus.edu.sg
Publication
1. Y. Li, H. Chai*, Z. Yuan, C. Huang, S. Wang, Y. Sun, X. Zhang, G. Zhang*, Metal–organic framework-engineered enzyme/nanozyme composites: Preparation, functionality, and sensing mechanisms. Chem. Eng. J. 2024, 496, 153884.
2. Y. Li, H. Chai*, Z. Yuan, Z. Zhang, Y. Zhao, K. Yu, Y. Sun, G. Zhang*, Zeolitic imidazolate framework-encapsulated zinc porphyrin photoresponsive nanozyme for colorimetric/fluorescent dual-mode sensing of glyphosate. Talanta 2024, 276, 126253.
3. H. Sun, J. Guan, H. Chai*, K. Yu, L. Qu, X. Zhang, G. Zhang*, Zinc porphyrin/MXene hybrids with phosphate-induced stimuli-responsive behavior for dual-mode fluorescent/electrochemiluminescent ratiometric biosensing. Biosens. Bioeletron. 2024, 251, 116080.
4. A. Boakye, K. Yu, H. Chai, T. Xu, L. S. Houston, B. K. Asinyo, X. Zhang, G. Zhang*, L. Qu*, Two-Dimensional Nickel Porphyrinic Metal–Organic Framework-Modified Electrode for Electrochemical Sensing. Langmuir 2024, 40, 2708–2718.
5. K. Yu, H. Chai*, H. Sun, X. Xiang, H. Zhao, M. Tian, L. Qu, G. Zhang*, X. Zhang*, A fluorescence analysis model for assessing the water stability of porphyrinic metal–organic frameworks. Sens. Actuators B Chem. 2024, 401, 135046.
6. H. Chai, Y. Li, K. Yu, Z. Yuan, G. Guan, W. Tan, J. Ma, X. Zhang, G. Zhang*, Two-Site Enhanced Porphyrinic Metal-Organic Framework Nanozymes and Nano-/Bioenzyme Confined Catalysis for Colorimetric/Chemiluminescent Dual-Mode Visual Biosensing. Anal. Chem. 2023, 95, 16383–16391.
7. H. Chai†, K. Yu†, Y. Zhao, Z. Zhang, S. Wang, C. Huang, X. Zhang, G. Zhang*, MOF-On-MOF Dual Enzyme-Mimic Nanozyme with Enhanced Cascade Catalysis for Colorimetric/Chemiluminescent Dual-Mode Aptasensing. Anal. Chem. 2023, 95, 10785–10794.
8. T. Yan†, G. Zhang†*, K. Yun, H. Chai, M. Tian, L. Qu*, H. Dong, X. Zhang, Smartphone light-driven zinc porphyrinic MOF nanosheets-based enzyme-free wearable photoelectrochemical sensor for continuous sweat vitamin C detection. Chem. Eng. J. 2023, 455, 140779.
9. K. Yu†, M. Li†, H. Chai, Q. Liu, X. Hai, M. Tian, L. Qu, T. Xu, G. Zhang*, X. Zhang, MOF-818 nanozyme-based colorimetric and electrochemical dual-mode smartphone sensing platform for in situ detection of H2O2 and H2S released from living cells. Chem. Eng. J. 2023, 451, 138321.
10. A. Boakye, K. Yu, B. K. Asinyo, H. Chai, T. Raza, T. Xu, G. Zhang*, L. Qu*, A Portable Electrochemical Sensor Based on Manganese Porphyrin-Functionalized Carbon Cloth for Highly Sensitive Detection of Nitroaromatics and Gaseous Phenol. Langmuir 2022, 38, 12058–12069.
11. G. Zhang, Y. Ma, H. Chai*, K. Yu, Y. Li, S. Wang, J. Ma, L. Qu, W. Tan*, X. Zhang, Porphyrinic metal–organic framework@alumina nanocomposite fluorescent probe: Two-stage stimuli-responsive behavior and phosphate sensing. Sens. Actuators B Chem. 2022, 370, 132395.
12. K. Yu†, G. Zhang†*, H. Chai, L. Qu, D. Shan, X. Zhang*, Two-stage ligand exchange in Mn(III)-based porphyrinic metal−organic frameworks for fluorescence water sensing. Sens. Actuators B Chem. 2022, 362, 131808.
13. G. Zhang*, M. Li, K. Yu, H. Chai*, S. Xu, T. Xu, L. Qu, X. Zhang*, Two-Dimensional Metalloporphyrinic Framework Nanosheet-Based Dual-Mechanism-Driven Ratiometric Electrochemiluminescent Biosensing of Protein Kinase Activity. ACS Appl. Bio Mater. 2021, 4, 1616–1623.
14. G. Zhang*, H. Chai, M. Tian, S. Zhu, L. Qu, X. Zhang*, Zirconium-Metalloporphyrin Frameworks-Luminol Competitive Electrochemiluminescence for Ratiometric Detection of Polynucleotide Kinase Activity. Anal. Chem. 2020, 92, 7354–7362.
15. G. Zhang, H. Dong, X. Zhang*, Fluorescence proximity assay based on a metal–organic framework platform. Chem. Commun. 2019, 55, 8158–8161.
16. G. Zhang, D. Shan, H. Dong, S. Cosnier, K.A. Al-Ghanem, Z. Ahmad, S. Mahboob, X. Zhang*, DNA-Mediated Nanoscale Metal-Organic Frameworks for Ultrasensitive Photoelectrochemical Enzyme-Free Immunoassay. Anal. Chem. 2018, 90, 12284–12291.
17. G.-Y. Zhang, Y.-H. Zhuang, D. Shan*, G.-F. Su, S. Cosnier, X.-J. Zhang*, Zirconium-Based Porphyrinic Metal-Organic Framework (PCN-222): Enhanced Photoelectrochemical Response and Its Application for Label-free Phosphoprotein Detection. Anal. Chem. 2016, 88, 11207–11212.
18. G.-Y. Zhang, C. Cai, S. Cosnier, H.-B. Zeng, X.-J. Zhang, D. Shan*, Zirconium–Metalloporphyrin Frameworks as a Three-in-One Platform Possessing Oxygen Nanocage, Electron Media, and Bonding Site for Electrochemiluminescence Protein Kinase Activity Assay. Nanoscale 2016, 8, 11649–11657.
19. G.-Y. Zhang, S.-Y. Deng*, X.-J. Zhang, D. Shan*, Cathodic electrochemiluminescence of singlet oxygen induced by the electroactive zinc porphyrin in aqueous media. Electrochim. Acta 2016, 190, 64–68.
20. G.-Y. Zhang, S.-Y. Deng, W.-R. Cai, S. Cosnier, X.-J. Zhang, D. Shan*, Magnetic Zirconium Hexacyanoferrate(II) Nanoparticle as Tracing Tag for Electrochemical DNA Assay. Anal. Chem. 2015, 87, 9093–9100.