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Zhichu Xiang

Research Fellow

Research interest

DNA & Peptide hybrid nanosystem for biomedical applications

Education background

Ph.D., Nanoscience and Technology, University of Chinese Academy of Sciences, 2019

B.Sc., Biotechnology, Jiangsu Ocean University, 2014

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Liang Zhao_edited_edited.jpg

E-mail: xiangzc@nus.edu.sg

Publication

  1. Xiang, Z.; Zhao, J.; Yi, D.; Di, Z.; Li, L.; PNA-Guided Peptide Engineering of Aptamer Sensor for Protease-Unlocked Molecular Imaging. Angew. Chem. Int. Ed. 2021, 60, 22659-22663.

  2. Xiang, Z.; Zhao, J.; Qu, J.; Song, J.; Li, L.; A Multivariate-Gated DNA Nanodevice for Pro-metastatic Biomolecules Imaging in Tumor Microenvironment. Angew. Chem. Int. Ed. 2022, 61,e202111836.

  3. Jiang, G.; Fan, D.; Xiang, Z.*; Fang, Q.*, Self-Confirming Magnetosomes for Tumor-Targeted T1/T2 Dual-Mode MR Imaging and MRI-Guided Photothermal Therapy. Adv. Healthc. Mater. 2022,14, e2200841

  4. Xiang, Z.; Liu, M.; Song, J., Stimuli-Responsive Polymeric Nanosystems for Controlled Drug Delivery. Appl. Sci. 2021, 11, 9541.

  5. Xiang, Z.; Jiang G.; Fan D.; Tian J.; Hu Z.; Fang Q., Drug-internalized bacterial swimmers for magnetically manipulable tumor-targeted drug delivery. Nanoscale 2020, 12, 13513-13522.

  6. Xiang, Z.; Jiang, G.; Yang, X.; Fan, D.; Nan, X.; Li, D.; Hu, Z.; Fang, Q., Peptosome coadministration improves tumor targeting and enrichment of nanoparticles through NRP1-mediated co-endocytosis. Biomolecules 2019, 9, 172.

  7. Xiang, Z.; Yang, X.; Jiang, G.; Fan, D.; Geng, L.; Wang, H.; Hu, Z.; Fang, Q., Design of a Simple and Practical Nanosystem Coordinates Tumor Targeting and Penetration for Improved Theranostics. Adv. Therap. 2019, 2, 1800107.

  8. Xiang, Z.; Yang, X.; Xu, J.; Lai, W.; Wang, Z.; Hu, Z.; Tian, J.; Geng, L.; Fang, Q., Tumor detection using magnetosome nanoparticles functionalized with a newly screened EGFR/HER2 targeting peptide. Biomaterials 2017, 115, 53-64.

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