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Fangfang Cao

Research Fellow

Research Interest

Nanocatalytic medicine & Microbial therapy

Education Background

Ph.D., Inorganic Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 2019

B.Sc., Chemistry, Nanjing Normal University, 2014

Liang Zhao_edited_edited.jpg

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E-mail: cffdc@nus.edu.sg

Publications


  1. Fangfang Cao, Lulu Jin, Yong Gao, Yuan Ding, Hongyang Wen, Zhefeng Qian, Chenyin Zhang, Liangjie Hong, Huang Yang, Jiaojiao Zhang, Zongrui Tong, Weilin Wang*, Xiaoyuan Chen*, Zhengwei Mao*. Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis. Nat. Nanotechnol., 2023, 18, 617-627.

  2. Fangfang Cao†, Lulu Jin†, Chenyin Zhang, Yong Gao, Zhefeng Qian, Hongyang Wen, Sisi Yang, Ziqiang Ye, Liangjie Hong, Huang Yang, Zongrui Tong, Liang Cheng, Yuan Ding, Weilin Wang, Guocan Yu*, Zhengwei Mao*, Xiaoyuan Chen*. Engineering clinically relevant probiotics with switchable “nano-promoter” and “nano-effector” for precise tumor therapy. Adv. Mater., 2023, DOI: 10.1002/adma.202304257.

  3. Chunxiong Zheng†, Qingguo Zhong†, Ke Yi, Huimin Kong, Fangfang Cao*, Chenya Zhuo, Yanteng Xu, Run Shi, Enguo Ju, Wantong Song, Yu Tao*, Xiaoyuan Chen*, Mingqiang Li*. Anti-phagocytosis-blocking repolarization-resistant membrane-fusogenic liposome (ARMFUL) for adoptive cell immunotherapy. Sci. Adv., 2023, 9, eadh2413.

  4. Yining Chen†, Tianshu Zou†, Gaoying Xin, Xin Liu, Yunan Yang, Liqi Wei, Biao Zhang, Pengcheng Yu, Yiping Ren, Yanlin Feng, Rui Chen*, Fangfang Cao*, Xiaoyuan Chen*, Yan Cheng*. Oxygen-Independent Synchronized ROS Generation and Hypoxia Prodrug Activation with Z-Scheme Heterostructure Sonosensitizer. Adv. Mater., 2023 (DOI: 10.1002/adma.202307929)

  5. Yanlin Feng†, Jianlin Wang†, Jimin Cao*, Fangfang Cao*, Xiaoyuan Chen*, Manipulating calcium homeostasis with nanoplatforms for enhanced cancer therapy. Exploration, 2023 (Invited, DOI: 10.1002/EXP.20230019)

  6. Yanlin Feng†, Xin Ning†, Jianlin Wang, Zhaoyang Wen, Fangfang Cao*, Qing You, Jianhua Zou, Xin Zhou, Teng Sun, Jimin Cao*, Xiaoyuan Chen*. Mace-like plasmonic Au-Pd heterostructures boost near-infrared photoimmunotherapy. Adv. Sci., 2023,10, 2204842.

  7. Yanlin Feng†, Jianlin Wang†, Xin Ning, Aiyun Li, Qing You, Wanzhen Su, Deping Wang, Jianyun Shi, Lan Zhou, Fangfang Cao*, Xiaoyuan Chen* and Jimin Cao*. BaTiO3@Au nanoheterostructure suppresses triple-negative breast cancer by persistently disrupting mitochondrial energy metabolism. Nano. Res., 2023, 16, 2775-2785.

  8. Fangfang Cao, Yanjuan Sang, Chaoying Liu*, Fuquan Bai, Lirong Zheng, Jinsong Ren*, and Xiaogang Qu*. Self-adaptive single-atom catalyst boosting selective ferroptosis in tumor cells. ACS Nano, 2022, 16, 855-868.

  9. Fangfang Cao, Lu Zhang, Yawen You, Lirong Zheng, Jinsong Ren*, and Xiaogang Qu*. An enzyme-mimicking single-atom catalyst as an efficient multiple reactive oxygen and nitrogen species scavenger for sepsis management. Angew. Chem. Int. Ed., 2020, 59, 5108-5115.

  10. Fangfang Cao, Lu Zhang, Huan Wang, Yawen You, Ying Wang*, Nan Gao, Jinsong Ren*, and Xiaogang Qu*. Defect-rich adhesive nanozymes as efficient “antibiotics” for enhanced bacterial inhibition. Angew. Chem. Int. Ed., 2019, 58, 2-9.

  11. Fangfang Cao, Enguo Ju, Yan Zhang, Zhenzhen Wang, Chaoqun Liu, Wei Li, Yanyan Huang, Kai Dong, Jinsong Ren*, and Xiaogang Qu*. An efficient and benign antimicrobial depot based on silver-infused MoS2. ACS Nano, 2017, 11, 4651-4659.

  12. Fangfang Cao, Yan Zhang, Yuhuan Sun, Zhenzhen Wang, Lu Zhang, Yanyan Huang, Chaoqun Liu, Zhen Liu, Jinsong Ren* and Xiaogang Qu*. Ultrasmall nanozymes isolated within porous carbonaceous frameworks for synergistic cancer therapy: enhanced oxidative damage and reduced energy supply. Chem. Mater., 2018, 30, 7831-7839.

  13. Fangfang Cao, Enguo Ju, Chaoqun Liu, Wei Li, Yan Zhang, Kai Dong, Zhen Liu，Jinsong Ren* and Xiaogang Qu*. Encapsulation of aggregated gold nanoclusters in a metal-organic framework for real-time monitoring of drug release. Nanoscale, 2017, 9, 4128-4134.

  14. Fangfang Cao, Enguo Ju, Chaoqun Liu, Fang Pu*, Jinsong Ren* and Xiaogang Qu*. Coupling a DNA-ligand ensemble with Ag cluster formation for the label-free and ratiometric detection of intracellular biothiols. Chem. Commun., 2016, 52, 5167-5170.


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