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Changrong Shi

Research Fellow

Research Interest

Modulation and imaging immune cell activity

Education Background

Ph.D., Biochemistry and Molecular Biology, Xiamen University, 2022

M.Sc., Translational Medicine, Xiamen University, 2018

Liang Zhao_edited_edited.jpg

B.Sc., Biotechnology, Guilin Medical University, 2015

E-mail: cr.shi@nus.edu.sg

Publications


  1. Shi C#, Zhang Q#, Yao Y, Zeng F, Du C, Nijiati S, Wen X, Zhang X, Yang H, Chen H, Guo Z, Zhang X, Gao J, Guo W*, Chen X*, Zhou Z*. Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics. Nat Nanotechnol 2023, 18(1): 86-97.

  2. Shi C#, Zhang X#, Liu X, Chen X*, Zhou Z*. Theranostics on the immunoactivity of T cells. Clin Transl Med 2023, 13(9):e1421.

  3. Shi C, Fu W, Zhang X, Zhang Q, Zeng F, Nijiati S, Du C, Liu X, Wang M, Yao Y, Huang H, Zheng N, Chen X, Wu B*, Zhou Z*. Boosting the immunoactivity of t cells by resonant thermal radiation from electric graphene films for improved cancer immunotherapy. Adv Ther 2022, 6(2): 2200163.

  4. Shi C, Zhou Z*, Lin H*, Gao J*. Imaging beyond seeing: early prognosis of cancer treatment. Small Methods 2021, 5(3): e2001025.

  5. Shi C#, Liu T#,*, Guo Z, Zhuang R, Zhang X*, Chen X*. Reprogramming tumor-associated macrophages by nanoparticle-based reactive oxygen species photogeneration. Nano Lett 2018, 18(11): 7330-7342.

  6. Wen X, Shi C, Zeng X, Zhao L, Yao L, Liu Z, Feng L, Zhang D, Huang J, Li Y, Lin Q, Chen H, Zhuang R, Chen X*, Zhang X*, Guo Z*. A paradigm of cancer immunotherapy based on 2-[18F]FDG and anti–pd-l1 mab combination to enhance the antitumor effect. Clin Cancer Res 2022, 28(13): 2923-2937.

  7. Zeng F, Nijiati S, Liu Y, Yang Q, Liu X, Zhang Q, Chen S, Su A, Xiong H, Shi C, Cai C, Lin Z, Chen X*, Zhou Z*. Ferroptosis MRI for early detection of anticancer drug–induced acute cardiac/kidney injuries. Sci Adv 2023, 9(10): eadd8539.

  8. Wen X, Shi C, Yang L, Zeng X, Lin X, Huang J, Li Y, Zhuang R, Zhu H, Guo Z*, Zhang X*. A radioiodinated FR-beta-targeted tracer with improved pharmacokinetics through modification with an albumin binder for imaging of macrophages in AS and NAFL. Eur J Nucl Med Mol Imaging 2022, 49(2): 503-516.

  9. Song M, Liu T*, Shi C, Zhang X*, Chen X*. Bioconjugated manganese dioxide nanoparticles enhance chemotherapy response by priming tumor-associated macrophages toward M1-like phenotype and attenuating tumor hypoxia. ACS Nano 2016, 10(1): 633-647.


Grants


  1. 2024 - 2026 The National Natural Science Foundation of China (grant no. 82302358)

  2. 2024 - 2027 The National Natural Science Foundation of China (grant no. 82360366)

  3. 2023 - 2025 The Postdoctoral Innovative Talent Support Program (grant no. BX20230200)

  4. 2022 - 2024 The China Postdoctoral Science Foundation (grant no. 2022M722654)

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