Selected Publications
Inhalation delivery of dexamethasone with iSEND nanoparticles attenuates the COVID-19 cytokine storm in mice and nonhuman primates.
Sci Adv. 2023 Jun 16;9(24):eadg3277.
Meng QF, Tai W, Tian M, Zhuang X, Pan Y, Lai J, Xu Y, Xu Z, Li M, Zhao G, Yu GT, Yu G, Chen R, Jin N, Li X, Cheng G, Chen X, Rao L.
Biomimetic nanovaccine-mediated multivalent IL-15 self-transpresentation (MIST) for potent and safe cancer immunotherapy.
Nat Commun. 2023 Oct 24;14(1):6748.
Wang K, Zhang X, Ye H, Wang X, Fan Z, Lu Q, Li S, Zhao J, Zheng S, He Z, Ni Q, Chen X, Sun J.
Redox-responsive polymer micelles co-encapsulating immune checkpoint inhibitors and chemotherapeutic agents for glioblastoma therapy.
Nat Commun. 2024 Feb 6;15(1):1118.
Zhang Z, Xu X, Du J, Chen X, Xue Y, Zhang J, Yang X, Chen X, Xie J, Ju S.
Nanomedicines for an Enhanced Immunogenic Cell Death-Based In Situ Cancer Vaccination Response.
Acc Chem Res. 2024 Mar 19;57(6):905-918.
Zhao C, Wang C, Shan W, Wang Z, Chen X, Deng H.
Polymeric nanocarrier via metabolism regulation mediates immunogenic cell death with spatiotemporal orchestration for cancer immunotherapy
Nat Commun. 2024 Oct 4;15(1):8586. doi: 10.1038/s41467-024-53010-0
Guo Y, Li Y, Zhang M, Ma R, Wang Y, Weng X, Zhang J, Zhang Z, Chen X, Yang W.
A DNA origami device spatially controls CD95 signalling to induce immune tolerance in rheumatoid arthritis
Nat. Mater. (2024). DOI:10.1038/s41563-024-01865-5
Ling Li, Jue Yin, Wen Ma, Longguang Tang, Jianhua Zou, Linzi Yang, Ting Du, Yi Zhao, Lianhui Wang, Zhen Yang, Chunhai Fan, Jie Chao & Xiaoyuan Chen
An in vitro-transcribed circular RNA
targets the mitochondrial inner membrane
cardiolipin to ablate EIF4G2+/PTBP1+
pan-adenocarcinoma
Nature Cancer, 2023, 10.1038/s43018-023-00650-8
Zunyong Feng, Xuanbo Zhang, Jing Zhou, Qiang Li, Liuxi Chu, Guangfu Di, Zhengyuan Xu, Qun Chen, Ming Wang, Xiaochun Jiang, Hongping Xia, Xiaoyuan Chen
Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis.
Nature nanotechnology, (2023) 10.1038/s41565-023-01346-x.
Cao, F., Jin, L., Gao, Y., Ding, Y., Wen, H., Qian, Z., Zhang, C., Hong, L., Yang, H., Zhang, J., Tong, Z., Wang, W., Chen, X., & Mao, Z.
Ferroptosis MRI for early detection of anticancer drug-induced acute cardiac/kidney injuries.
Science advances, 9(10), eadd8539.
Zeng, F., Nijiati, S., Liu, Y., Yang, Q., Liu, X., Zhang, Q., Chen, S., Su, A., Xiong, H., Shi, C., Cai, C., Lin, Z., Chen, X., & Zhou, Z.
Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics
Nat. Nanotechnol. (2022). https://doi.org/10.1038/s41565-022-01261-7
Changrong Shi, Qianyu Zhang, Yuying Yao, Fantian Zeng, Chao Du, Sureya Nijiati, Xuejun Wen, Xinyi Zhang, Hongzhang Yang, Haoting Chen, Zhide Guo, Xianzhong Zhang, Jinhao Gao, Weisheng Guo, Xiaoyuan Chen & Zijian Zhou
A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy
Nat Commun. 2021;12(1):523.
Tang W, Yang Z, He L, Deng L, Fathi P, Zhu S, Li L, Shen B, Wang Z, Jacobson O, Song J, Zou J, Hu P, Wang M, Mu J, Cheng Y, Ma Y, Tang L, Fan W, Chen X
Hybrid Membrane-Decorated Prussian Blue for Effective Cancer Immunotherapy via Tumor-Associated Macrophages Polarization and Hypoxia Relief
Adv Mater, 2022, 34, 2200389
Hou L, Gongu X, Zhang JH, Yang W, Chen X
