Publications in 2022
974
Alpha-peptide receptor radionuclide therapy using actinium-225 labeled somatostatin receptor agonists and antagonists
Front Med (Lausanne). 2022 Dec 7;9:1034315
Mengqi Shi, Vivianne Jakobsson, Lukas Greifenstein, Pek-Lan Khong, Xiaoyuan Chen, Richard P Baum, Jingjing Zhang
973
PET imaging of fibroblast activation protein in various types of cancers by using 68Ga-FAP-2286: Comparison with 18F-FDG and 68Ga-FAPI-46 in a single-center, prospective study.
J Nucl Med. 2022 Sep 2:jnumed.122.264544.
Pang Y, Zhao L, Meng T, Xu W, Lin Q, Wu H, Zhang J, Chen X, Sun L, Chen H.
972
Synergism of 64Cu-Labeled RGD with Anti-PD-L1 Immunotherapy for the Long-Acting Antitumor Effect.
Bioconjug Chem. 2022 Nov 16;33(11):2170-2179.
Wen X, Zeng X, Liu J, Zhang Y, Shi C, Wu X, Zhuang R, Chen X, Zhang X, Guo Z.
971
Development of a multi-scene universal multiple wavelet-FFT algorithm (MW-FFTA) for denoising motion artifacts in OCT-angiography in vivo imaging.
Opt Express. 2022 Sep 26;30(20):35854-35870.
Zhang Y, Li J, Liu C, Zheng K, Zhang B, Zhou Y, Dai C, Fan S, Yao Y, Zhuang R, Guo D, Huang Z, Mao J, Liang J, Yang H, Wang L, Liu G, Chen X, Zhao Q.
970
A Totipotent "All-In-One" Peptide Sequentially Blocks Immune Checkpoint and Reverses the Immunosuppressive Tumor Microenvironment.
Adv Mater. 2022 Oct 19:e2207330.
Zhang L, Jiang Z, Yang X, Qian Y, Wang M, Wu S, Li L, Jia F, Wang Z, Hu Z, Zhao M, Tang X, Li G, Shang H, Chen X, Wang W.
969
Near-infrared-II ratiometric fluorescence probes for non-invasive detection and precise navigation surgery of metastatic sentinel lymph nodes.
Theranostics. 2022 Oct 9;12(16):7191-7202.
Li M, Zheng X, Han T, Ma S, Wang Y, Sun B, Xu J, Wang X, Zhang S, Zhu S, Chen X.
968
Synthesis, preclinical evaluation and radiation dosimetry of a dual targeting PET tracer [68Ga]Ga-FAPI-RGD.
Theranostics. 2022 Oct 9;12(16):7180-7190.
Zang J, Wen X, Lin R, Zeng X, Wang C, Shi M, Zeng X, Zhang J, Wu X, Zhang X, Miao W, Xu P, Guo Z, Zhang J, Chen X.
967
Cell Wall Destruction and Internal Cascade Synergistic Antifungal Strategy for Fungal Keratitis.
ACS Nano. 2022 Nov 22;16(11):18729-18745.
Ye Y, He J, Wang H, Li W, Wang Q, Luo C, Tang X, Chen X, Jin X, Yao K, Zhou M.
966
Biomimetic Yolk-Shell Nanocatalysts for Activatable Dual-Modal-Image-Guided Triple-Augmented Chemodynamic Therapy of Cancer.
ACS Nano. 2022 Nov 22;16(11):19038-19052.
Pan Y, Zhu Y, Xu C, Pan C, Shi Y, Zou J, Li Y, Hu X, Zhou B, Zhao C, Gao Q, Zhang J, Wu A, Chen X, Li J.
965
An Integrated Polymeric mRNA Vaccine without Inflammation Side Effects for Cellular Immunity Mediated Cancer Therapy.
Adv Mater. 2022 Nov 3:e2207471
Huang P, Jiang L, Pan H, Ding L, Zhou B, Zhao M, Zou J, Li B, Qi M, Deng H, Zhou Y, Chen X.
964
A single-arm, low-dose, prospective study of 177Lu-EB-PSMA radioligand therapy in patients with metastatic castration-resistant prostate cancer.
J Nucl Med. 2022 Nov 3:jnumed.122.264857.
Wang G, Zang J, Jiang Y, Liu Q, Sui H, Wang R, Fan X, Zhang J, Zhu Z, Chen X.
963
Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection.
Chem Soc Rev. 2022 Nov 28;51(23):9759-9830.
Pan Y, Tang W, Fan W, Zhang J, Chen X.
962
Responsive Accumulation of Nanohybrids to Boost NIR-Phototheranostics for Specific Tumor Imaging and Glutathione Depletion-Enhanced Synergistic Therapy.
Adv Sci (Weinh). 2022 Nov 14;10(1):e2205208.
He L, Zheng N, Wang Q, Du J, Wang S, Cao Z, Wang Z, Chen G, Mu J, Liu S, Chen X.
961
Facile Synthesis of Weakly Ferromagnetic Organogadolinium Macrochelates-Based T1 -Weighted Magnetic Resonance Imaging Contrast Agents.
Adv Sci (Weinh). 2022 Nov 15;10(1):e2205109.
Lu Y, Liang Z, Feng J, Huang L, Guo S, Yi P, Xiong W, Chen S, Yang S, Xu Y, Li Y, Chen X, Shen Z.
960
In Response to Precision Medicine: Current Subcellular Targeting Strategies for Cancer Therapy.
Adv Mater. 2022 Nov 29:e2209529
Li Z, Zou J, Chen X.
959
Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics
Nat Nanotechnol. 2022 Dec 19. doi: 10.1038/s41565-022-01261-7
Shi C, Zhang Q, Yao Y, Zeng F, Du C, Nijiati S, Wen X, Zhang X, Yang H, Chen H, Guo Z, Zhang X, Gao J, Guo W, Chen X, Zhou Z. Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics. Nat Nanotechnol. 2022 Dec 19. doi: 10.1038/s41565-022-01261-7. Epub ahead of print. PMID: 36536041.
958
Evolution of drug regulations and regulatory innovation for anticancer drugs in China.
Acta Pharm Sin B. 2022 Dec;12(12):4365-4377
Liu Y, Zhang N, Xie C, Jiang Y, Qin Y, Zhou L, Fan Y, Ren L, Yin C, Yang H, Xie W, Zhai Q, Li G, Chen H, Chen X.
957
Safety and efficacy of peptide receptor radionuclide therapy with 177Lu-DOTA-EB-TATE in patients with metastatic neuroendocrine tumors
Theranostics 2022; 12(15):6437-6445.
Jiang Y, Liu Q, Wang G, Sui H, Wang R, Wang J, Zhang J, Zhu Z, Chen X.
956
Organic phosphorescent nanoscintillator for low-dose X-ray-induced photodynamic therapy.
Nat Commun. 2022;13(1):5091.
Wang X, Sun W, Shi H, Ma H, Niu G, Li Y, Zhi J, Yao X, Song Z, Chen L, Li S, Yang G, Zhou Z, He Y, Qu S, Wu M, Zhao Z, Yin C, Lin C, Gao J, Li Q, Zhen X, Li L, Chen X, Liu X, An Z, Chen H, Huang W.
954
A pilot study of 68 Ga-PSMA-617 PET/CT imaging and 177Lu-EB-PSMA-617 radioligand therapy in patients with adenoid cystic carcinoma.
EJNMMI Res. 2022 Aug 19;12(1):52.
Wang G, Zhou M, Zang J, Jiang Y, Chen X, Zhu Z, Chen X.
953
Combined 18F-FDG and 18F-Alfatide II PET May Predict Luminal B (HER2 Negative) Subtype and Nonluminal Subtype of Invasive Breast Cancer.
Mol Pharm. 2022 Aug 16. doi: 10.1021/acs.molpharmaceut.2c00547.
Wu J, Zhang X, Jia Z, Zhou X, Qi R, Ji H, Sun J, Sun C, Teng Z, Lu G, Chen X.
952
Cancer Nanomedicine
Nat Rev Cancer, doi: 10.1038/s41568-022-00496-9
Bhatia S, Chen X, Dobrovolskaia M, Lammers T
951
Management of fluorescent organic/inorganic nanohybrids for biomedical applications in the NIR-II region
Chem Soc Rev, DOI https://doi.org/10.1039/D2CS00131D
Li B, Zhao M, Lin J, Huang P, Chen X
950
Microfluidics-Assisted Fluorescence Mapping of DNA Phosphorothioation
Anal Chem, 2022 Jul 26;94(29):10479-10486
Huang Q, Chen X, Meng Q-F, Yue L, Jiang W, Zhao X-Z, Rao L, Chen X, S chen
949
Harnessing Immune Response Using Reactive Oxygen Species-Generating/Eliminating Inorganic Biomaterials for Disease Treatment
Adv Drug Deliv Rev, 2022 Jul 16;188:114456
Zhao C, Deng H, Chen X
948
Super-stable cyanine@albumin fluorophore for enhanced NIR-II bioimaging
Theranostics. 2022 May 26;12(10):4536-4547
Bai L, Hu Z, Han T, Wang Y, Xu J, Jiang G, Feng X, Sun B, Liu X, Tian R, Sun H, Zhang S, Chen X, Zhu S.
947
Nanomaterial-Mediated Ablation Therapy for Cancer Stem Cells
Matter, 2022;5: 1367-1390.
Pan Y, Liu L, Rao L, Chen X
946
Chiral gold clusters functionalized two-dimensional nanoparticle films to regulate the adhesion and differentiation of stem cells
J Colloid Interface Sci. 2022;625:831-838.
Kang X, Wang Y, Cai XL, Hua Y, Shao ZH, Chen X, Zhao X, Zang SQ.
945
Cucurbituril-based Supramolecular Polymers for Biomedical Applications
Angew Chem Int Ed Engl. 2022 Jun 28. doi: 10.1002/anie.202206763.
Wang Z, Sun C, Yang K, Chen X, Wang R.
944
The Roles of Polymers in mRNA Delivery
Matter, 2022;5:1670-1699.
Huang P, Deng H, Zhou Y, Chen X
943
Levonorgestrel-protected Au8 and Au10 clusters with different antimicrobial abilities
J Mater Chem B. 2022 Jun 20. doi: 10.1039/d2tb00533f.
Wang Y, Hua Y, Shao ZH, Chen X, Zhao X, Zang SQ.
942
Composition-Dependent Enzyme Mimicking Activity and Radiosensitizing Effect of Bimetallic Clusters to Modulate Tumor Hypoxia for Enhanced Cancer Therapy
Adv Mater. 2022:e2203734.
Hua Y, Huang JH, Shao ZH, Luo XM, Wang ZY, Liu JQ, Zhao X, Chen X, Zang SQ.
941
PD-L1-Targeted Radionuclide Therapy Combined with αPD-L1 Antibody Immunotherapy Synergistically Improves the Antitumor Effect
Mol Pharm. 2022 Jun 2. doi: 10.1021/acs.molpharmaceut.2c00281.
Wen X, Zeng X, Cheng X, Zeng X, Liu J, Zhang Y, Li Y, Chen H, Huang J, Guo Z, Chen X, Zhang X.
940
Rational Design and Pharmacomodulation of Protein-Binding Theranostic Radioligands for Targeting the Fibroblast Activation Protein
J Med Chem. 2022 Jun 5. doi: 10.1021/acs.jmedchem.1c02162.
Meng L, Fang J, Zhao L, Wang T, Yuan P, Zhao Z, Zhuang R, Lin Q, Chen H, Chen X, Zhang X, Guo Z.
939
A genetic engineering strategy for editing near-infrared-II fluorophores.
Nat Commun. 2022 May 23;13(1):2853.
Tian R, Feng X, Wei L, Dai D, Ma Y, Pan H, Ge S, Bai L, Ke C, Liu Y, Lang L, Zhu S, Sun H, Yu Y, Chen X.
938
Protective Effect of Platinum Nano-antioxidant and Nitric Oxide Against Hepatic Ischemia-Reperfusion Injury
Nat Commun, 2022;13(1):2513
Mu J, Li C, Shi Y, Liu G, Zou J, Zhang D, Jiang C, Wang X, He L, Huang P, Yin Y, Chen X
937
Reactive Oxygen Species Scavenging Nanomedicine for The Treatment of Ischemic Heart Disease
Adv Mater. 2022:e2202169.
Zhang Z, Dalan R, Hu Z, Wang JW, Chew NW, Poh KK, Tan RS, Soong TW, Dai Y, Ye L, Chen X.
936
Photoacoustic Imaging-Guided Synergistic Photothermal/Radiotherapy Using Plasmonic Bi/Bi2O3-x Nanoparticles
Adv Funct Mater, https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202113353
Huang X, Zha F, Zou J, Li Y, Wang F, Chen X
935
Smart Mushroom-Inspired Imprintable and Lightly Detachable (MILD) Microneedle Patterns for Effective COVID-19 Vaccination and Decentralized Information Storage
ACS Nano. 2022 Apr 22. doi: 10.1021/acsnano.1c10718.
Li Q, Xu R, Fan H, Xu J, Xu Y, Cao P, Zhang Y, Liang T, Zhang Y, Chen W, Wang Z, Wang L, Chen X
934
A nanovaccine for antigen self-presentation and immunosuppression reversal as a personalized cancer immunotherapy strategy
Nat Nanotechnol. 2022 Apr 11. doi: 10.1038/s41565-022-01098-0.
Liu C, Liu X, Xiang X, Pang X, Chen S, Zhang Y, Ren E, Zhang L, Liu X, Lv P, Wang X, Luo W, Xia N, Chen X, Liu G
933
Avoiding the self-nucleation interference: a pH-regulated gold in situ growth strategy to enable ultrasensitive immunochromatographic diagnostics
Theranostics. 2022;12(6):2801-2810.
Duan H, Ma T, Huang X, Gao B, Zheng L, Chen X, Xiong Y, Chen X
932
Combined Probe Strategy to Increase the Enzymatic Digestion Rate and Accelerate the Renal Radioactivity Clearance of Peptide Radiotracers
Mol Pharm. 2022 Mar 31. doi: 10.1021/acs.molpharmaceut.2c00051.
Zhang M, Ye J, Xie Z, Wang Y, Ma W, Kang F, Yang W, Wang J, Chen X
931
A paradigm of cancer immunotherapy based on 2-[18F]FDG and anti-PD-L1 mAb combination to enhance the anti-tumor effect
Clin Cancer Res. 2022 Mar 23:clincanres.0159.2022.
Wen X, Shi C, Zeng X, Zhao L, Yao L, Liu Z, Feng L, Zhang D, Huang J, Li Y, Lin Q, Chen H, Zhuang R, Chen X, Zhang X, Guo Z.
930
Preliminary Clinical Application of RGD-Containing Peptides as PET Radiotracers for Imaging Tumors
Front Oncol. 2022;12:837952.
Li L, Chen X, Yu J, Yuan S.
929
A tumor microenvironment dual responsive contrast agent for contrary contrast-magnetic resonance imaging and specific chemotherapy of tumors
Nanoscale Horiz. 2022 Feb 25. doi: 10.1039/d1nh00632k.
Lu Y, Feng J, Liang Z, Lu X, Guo S, Huang L, Xiong W, Chen S, Zhou H, Ma X, Xu Y, Qiu X, Wu A, Chen X, Shen Z.
928
A super-stable homogeneous Lipiodol-hydrophilic chemodrug formulation for treatment of hepatocellular carcinoma
Theranostics. 2022;12(4):1769-1782.
He P, Ren E, Chen B, Chen H, Cheng H, Gao X, Liang X, Liu H, Li J, Li B, Chen A, Chu C, Chen X, Mao J, Zhang Y, Liu G.
927
Recent advances in biomaterial-boosted adoptive cell therapy
Chem Soc Rev. 2022 Feb 16. doi: 10.1039/d1cs00786f.
Xue Y, Che J, Ji X, Li Y, Xie J, Chen X.
926
A "Self-Checking" pH/Viscosity-Activatable NIR-II Molecule for Real-Time Evaluation of Photothermal Therapy Efficacy
Angew Chem Int Ed Engl. 2022 Feb 15. doi: 10.1002/anie.202200025.
Li B, Liu H, He Y, Zhao M, Ge C, Younis MR, Huang P, Chen X, Lin J.
925
Antibody-Incorporated Nanomedicines for Cancer Therapy
Adv Mater. 2022 Feb 10:e2109210. doi: 10.1002/adma.202109210.
Wu SY, Wu FG, Chen X.
924
18F-Alfatide II for the evaluation of axillary lymph nodes in breast cancer patients: comparison with 18F-FDG
Eur J Nucl Med Mol Imaging. 2022 Feb 9. doi: 10.1007/s00259-021-05333-z.
Wu J, Tian J, Zhang Y, Ji H, Sun J, Wang X, Sun C, Wang L, Teng Z, Lu G, Zhu H, Chen X.
923
Noninvasive Dual-Modality Photoacoustic-Ultrasonic Imaging to Detect Mammalian Embryo Abnormalities after Prenatal Exposure to Methylmercury Chloride (MMC): A Mouse Study
Environ Health Perspect. 2022;130(2):27002.
Qiu Q, Huang Y, Zhang B, Huang D, Chen X, Fan Z, Lin J, Yang W, Wang K, Qu N, Li J, Li Z, Huang J, Li S, Zhang J, Liu G, Rui G, Chen X, Zhao Q
922
Hybrid Membrane-Decorated Prussian Blue for Effective Cancer Immunotherapy via Tumor-Associated Macrophages Polarization and Hypoxia Relief
Adv Mater. 2022 Feb 1:e2200389.
Hou L, Gongu X, Zhang JH, Yang W, Chen X
921
Metal-free bioorthogonal click chemistry in cancer theranostics
Chem Soc Rev. 2022 Jan 20. doi: 10.1039/d1cs00451d.
Wu D, Yang K, Zhang Z, Feng Y, Rao L, Chen X, Yu G.
920
Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics
Theranostics. 2022;12(1):422-433.
Wen X, Xu P, Shi M, Liu J, Zeng X, Zhang Y, Shi C, Li J, Guo Z, Zhang X, Khong PL, Chen X.
919
Near-infrared probes for luminescence lifetime imaging
Nanotheranostics. 2022;6(1):91-102.
Li B, Lin J, Huang P, Chen X.
918
Coordinating the mechanism of actions of ferroptosis and photothermal effect for cancer theranostics
Angew Chem Int Ed Engl. 2021 Dec 21. doi: 10.1002/anie.202112925.
Zeng F, Tang L, Zhang Q, Shi C, Huang Z, Nijiati S, Chen X, Zhou Z.
917
Biodegradable Metal-Organic Framework-Gated Organosilica for Tumor Microenvironment-Unlocked Glutathione Depletion-Enhanced Synergistic Therapy
Adv Mater. 2021 Dec 13:e2107560. doi: 10.1002/adma.202107560.
Ma Y, Su Z, Zhou L, He L, Hou Z, Zou J, Cai Y, Chang D, Xie J, Zhu C, Fan W, Chen X, Ju S.
916
Prostate-specific membrane antigen radioligand therapy using 177Lu-PSMA I&T and 177Lu-PSMA-617 in patients with metastatic castration-resistant prostate cancer: comparison of safety, biodistribution and dosimetry
J Nucl Med. 2021 Dec 9:jnumed.121.262713. doi: 10.2967/jnumed.121.262713.
Schuchardt C, Zhang J, Kulkarni HR, Chen X, Mueller D, Baum RP.
915
The Chemistry of Organic Contrast Agents in the NIR-II Window
Angew Chem Int Ed Engl. 2021 Dec 6. doi: 10.1002/anie.202114722.
Mu J, Xiao M, Shi Y, Geng X, Li H, Yin Y, Chen X.
914
Nanomaterials targeting tumor associated macrophages for cancer immunotherapy
J Control Release. 2022;341:272-284.
Zhao C, Pang X, Yang Z, Wang S, Deng H, Chen X.
913
A generic self-assembly approach towards phototheranostics for NIR-II fluorescence imaging and phototherapy
Acta Biomater. 2021 Nov 20:S1742-7061(21)00769-8.
Cui C, Wang C, Fu Q, Song J, Zou J, Li L, Zhu J, Huang W, Li L, Yang Z, Chen X.