Publications in 2021
912
A multifunctional AIE gold cluster-based theranostic system: tumor-targeted imaging and Fenton reaction-assisted enhanced radiotherapy
J Nanobiotechnology. 2021;19(1):438.
Hua Y, Wang Y, Kang X, Xu F, Han Z, Zhang C, Wang ZY, Liu JQ, Zhao X, Chen X, Zang SQ.
911
Multi-Responsive Bottlebrush-Like Unimolecules Self-Assembled Nano-Riceball for Synergistic SonoChemotherapy
Small Methods. 2021;5(3):e2000416.
Shi X, Zhang Y, Tian Y, Xu S, Ren E, Bai S, Chen X, Chu C, Xu Z, Liu G.
910
Repurposing ICG enables MR/PA imaging signal amplification and iron depletion for iron-overload disorders
Sci Adv. 2021;7(51):eabl5862.
Lin H, Zhou Y, Wang J, Wang H, Yao T, Chen H, Zheng H, Zhang Y, Ren E, Jiang L, Chu C, Chen X, Mao J, Wang F, Liu G.
909
NIR-II emissive AIEgen photosensitizers enable ultrasensitive imaging-guided surgery and phototherapy to fully inhibit orthotopic hepatic tumors
J Nanobiotechnology. 2021;19(1):419.
Jia R, Xu H, Wang C, Su L, Jing J, Xu S, Zhou Y, Sun W, Song J, Chen X, Chen H.
908
Ligand Engineering of Titanium-Oxo Nanoclusters for Cerenkov Radiation-Reinforced Photo/Chemodynamic Tumor Therapy
ACS Appl Mater Interfaces. 2021;13(46):54727-54738.
Li J, Dai S, Qin R, Shi C, Ming J, Zeng X, Wen X, Zhuang R, Chen X, Guo Z, Zhang X.
907
Redox-Activated Contrast-Enhanced T1-Weighted Imaging Visualizes Glutathione-Mediated Biotransformation Dynamics in the Liver
ACS Nano. 2021;15:17831-17841.
Liu K, Kang B, Luo X, Yang Z, Sun C, Li A, Fan Y, Chen X, Gao J, Lin H.
906
Aptamer-based biosensors and application in tumor theranostics
Cancer Sci. 2022;113:7-16.
Mo T, Liu X, Luo Y, Zhong L, Zhang Z, Li T, Gan L, Liu X, Li L, Wang H, Sun X, Fan D, Qian Z, Wu P, Chen X.
905
Intelligent Pore Switch of Hollow Mesoporous Organosilica Nanoparticles for High Contrast Magnetic Resonance Imaging and Tumor-Specific Chemotherapy
Nano Lett. 2021;21(22):9551-9559.
Huang L, Feng J, Fan W, Tang W, Rong X, Liao W, Wei Z, Xu Y, Wu A, Chen X, Shen Z.
904
Polyprodrug Nanomedicines: An Emerging Paradigm for Cancer Therapy
Adv Mater. 2021 Oct 25:e2107434.
Yang K, Yang Z, Yu G, Nie Z, Wang R, Chen X.
903
Somatostatin receptor imaging with [68Ga]Ga-DOTATATE positron emission tomography/computed tomography (PET/CT) in patients with nasopharyngeal carcinoma
Eur J Nucl Med Mol Imaging. 2021 Oct 19. doi: 10.1007/s00259-021-05587-7.
Zhao L, Pang Y, Wang Y, Chen J, Zhuang Y, Zhang J, Zhao L, Sun L, Wu H, Chen X, Lin Q, Chen H.
902
Genetically Programmable Fusion Cellular Vesicles for Cancer Immunotherapy
Angew Chem Int Ed Engl. 2021;60(50):26320-26326.
Meng QF, Zhao Y, Dong C, Liu L, Pan Y, Lai J, Liu Z, Yu GT, Chen X, Rao L.
901
Smart Chemical Engineering-based Lightweight and Miniaturized Attachable Systems for Advanced Drug Delivery and Diagnostics
Adv Mater. 2021 Oct 13:e2106701.
Chen W, Wang Z, Wang L, Chen X.
900
Radioiodinated 4-(p-Iodophenyl) Butanoic Acid-Modified Estradiol Derivative for ER Targeting SPECT Imaging
Anal Chem. 2021;93(41):13998-14006.
Xu D, Lin X, Zeng X, Wen X, Li J, Li Y, Huang J, Chen X, Guo Z, Zhang X.
899
Lung-Targeting Lysostaphin Microspheres for Methicillin-Resistant Staphylococcus aureus Pneumonia Treatment and Prevention
ACS Nano. 2021;15(10):16625-16641.
Lin X, He J, Li W, Qi Y, Hu H, Zhang D, Xu F, Chen X, Zhou M.
898
Manipulating Intratumoral Fenton Chemistry for Enhanced Chemodynamic and ChemodynamicSynergized Multimodal Therapy
Adv Mater. 2021 Sep 27:e2104223.
Zhou Y, Fan S, Feng L, Huang X, Chen X.
897
Singlet Oxygen "Afterglow" Therapy with NIR-II Fluorescent Molecules
Adv Mater. 2021 Sep 13:e2103627.
Zou J, Li L, Zhu J, Li X, Yang Z, Huang W, Chen X.
896
Optimization of Enzymolysis Clearance Strategy To Enhance Renal Clearance of Radioligands
Bioconjug Chem. 2021 Sep 6. doi: 10.1021/acs.bioconjchem.1c00392.
Zhang M, Ye J, Xie Z, Yan Y, Wang J, Chen X.
895
Endogenous dual stimuli-activated NO generation in the conventional outflow pathway for precision glaucoma therapy
Biomaterials. 2021;277:121074.
Fan W, Song M, Li L, Niu L, Chen Y, Han B, Sun X, Yang Z, Lei Y, Chen X.
894
Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota
Theranostics. 2021;11(17):8570-8586.
Tong L, Hao H, Zhang Z, Lv Y, Liang X, Liu Q, Liu T, Gong P, Zhang L, Cao F, Pastorin G, Lee CN, Chen X, Wang JW, Yi H.
893
Fluorescence imaging of pathophysiological microenvironments.
Chem Soc Rev. 2021 Jul 1. doi: 10.1039/d1cs00083g.
Wang S, Ren WX, Hou JT, Won M, An J, Chen X, Shu J, Kim JS.
892
Exquisite vesicular nanomedicine by paclitaxel mediated co-assembly with camptothecin prodrug.
Angew Chem Int Ed Engl. 2021 Jul 18. doi: 10.1002/anie.202108658.
Zhou Z, Du C, Zhang Q, Yu G, Zhang F, Chen X.
891
Antiangiogenesis Combined with Inhibition of the Hypoxia Pathway Facilitates Low-Dose, X-rayInduced Photodynamic Therapy
ACS Nano. 2021 Jun 25. doi: 10.1021/acsnano.1c01063.
Jiang Z, He L, Yu X, Yang Z, Wu W, Wang X, Mao R, Cui D, Chen X, Li W.
890
Intravital Whole-Process Monitoring Thermo-Chemotherapy Via 2D Silicon Nanoplatform: A Macro Guidance and Long-Term Microscopic Precise Imaging Strategy
Adv Sci (Weinh). 2021 Jun 24:e2101242.
Huang D, Wang G, Mao J, Liu C, Fan Z, Zhang Y, Zhang B, Zhao Y, Dai C, He Y, Ma H, Liu G, Chen X, Zhao Q.
889
Mn3+-rich oxide/persistent luminescence nanoparticles achieve light-free generation of singlet oxygen and hydroxyl radicals for responsive imaging and tumor treatment
Theranostics. 2021 May 25;11(15):7439-7449.
Ding D, Feng Y, Qin R, Li S, Chen L, Jing J, Zhang C, Sun W, Li Y, Chen X, Chen H.
888
Functional Micro-/Nanomaterials for Multiplexed Biodetection
Adv Mater. 2021 Jun 17:e2004734.
7. Liu X, Wu W, Cui D, Chen X, Li W.
887
68Ga-NOTA-Evans Blue PET/CT findings in lymphangioleiomyomatosis compared with 99mTC-ASC lymphoscintigraphy: a prospective study.
Orphanet J Rare Dis. 2021 Jun 16;16(1):279
Hou G, Jiang Y, Xu W, Zhu Z, Huo L, Chen X, Li F, Xu KF, Cheng W.
886
Synthesis and Bioapplications of Ag2S Quantum Dots with Near-Infrared Fluorescence
Adv Mater. 2021 Jun 12:e2007768.
Ding C, Huang Y, Shen Z, Chen X
885
A Fluorinated Ionic Liquid-Based Activatable 19F MRI Platform Detects Biological Targets
Chem. 2020 May 14;6(5):1134-1148.
Zhu X, Tang X, Lin H, Shi S, Xiong H, Zhou Q, Li A, Wang Q, Chen X, Gao J.
884
A hypoxia responsive nanoassembly for tumor specific oxygenation and enhanced sonodynamic therapy
Biomaterials. 2021 May 3;275:120822.
Yang K, Yue L, Yu G, Rao L, Tian R, Wei J, Yang Z, Sun C, Zhang X, Xu M, Yuan Z, Chen X, Wang R.
883
Supramolecular Polymerization-Induced Nanoassemblies for Self-Augmented Cascade Chemotherapy and Chemodynamic Therapy of Tumour
Angew Chem Int Ed Engl. 2021 May 26. doi: 10.1002/anie.202103721.
Yang K, Yang Z, Yue L, Yu G, Zhang X, Sun C, Wei J, Rao L, Chen X, Wang R.
882
Photodynamic-Chemodynamic Cascade Reactions for Efficient Drug Delivery and Enhanced Combination Therapy
Adv Sci (Weinh). 2021 Apr 8;8(10):2002927.
Wang S, Yu G, Yang W, Wang Z, Jacobson O, Tian R, Deng H, Lin L, Chen X.
881
Extracellular vesicles as a drug delivery system:A systematic review of preclinical studies
Adv Drug Deliv Rev. 2021 May 18:S0169-409X(21)00175-7. doi: 10.1016/j.addr.2021.05.011.
Escudé Martinez de Castilla P, Tong L, Huang C, Marios Sofias A, Pastorin G, Chen X, Storm G, Schiffelers RM, Wang JW.
880
Beyond Photo: Xdynamic Therapies in Fighting Cancer.
Adv Mater. 2021:e2007488.
Wang S, Tian R, Zhang X, Cheng G, Yu P, Chang J, Chen X.
879
Bombesin-Tethered Reactive Oxygen Species (ROS)-Responsive Nanoparticles for Monomethyl Auristatin F (MMAF) Delivery
Bioengineering (Basel). 2021 Mar 29;8(4):43.
Kim J, Kim JS, Min KH, Kim YH, Chen X
878
Capturing Cytokines with Advanced Materials: A Potential Strategy to Tackle COVID-19 Cytokine Storm
Adv Mater. 2021 Apr 10:e2100012. doi: 10.1002/adma.202100012.
7. Meng QF, Tian R, Long H, Wu X, Lai J, Zharkova O, Wang JW, Chen X, Rao L.
877
Singlet Oxygen Generation in Dark-Hypoxia by Catalytic Microenvironment-Tailored Nanoreactors for NIR-II Fluorescence-Monitored Chemodynamic Therapy
Angew Chem Int Ed Engl. 2021 Apr 19. doi: 10.1002/anie.202102097.
Chen T, Hou P, Zhang Y, Ao R, Su L, Jiang Y, Zhang Y, Cai H, Wang J, Chen Q, Song J, Lin L, Yang H, Chen X.
876
Polyphenol-Containing Nanoparticles: Synthesis, Properties, and Therapeutic Delivery
Adv Mater. 2021 Apr 19:e2007356.
Guo Y, Sun Q, Wu FG, Dai Y, Chen X.
875
Rationally Programming Nanomaterials with DNA for Biomedical Applications
Adv Sci (Weinh). 2021 Feb 24;8(8):2003775.
He L, Mu J, Gang O, Chen X.
874
Biphasic synthesis of biodegradable urchin-like mesoporous organosilica nanoparticles for enhanced cellular internalization and precision cascaded therapy
Biomater Sci. 2021 Feb 17. doi: 10.1039/d1bm00015b.
Cheng Y, Jiao X, Wang Z, Jacobson O, Aronova MA, Ma Y, He L, Liu Y, Tang W, Deng L, Zou J, Yang Z, Zhang M, Wen Y, Fan W, Chen X
873
Targeted Dual Small Interfering Ribonucleic Acid Delivery via Non-Viral Polymeric Vectors for Pulmonary Fibrosis Therapy
Adv Mater. 2021:e2007798.
Ji Q, Hou J, Yong X, Gong G, Muddassir M, Tang T, Xie J, Fan W, Chen X
872
Supramolecular cancer nanotheranostics.
Chem Soc Rev. 2021 Feb 1. doi: 10.1039/d0cs00011f.
Zhou J, Rao L, Yu G, Cook TR, Chen X, Huang F.
871
Pnictogen Semimetal (Sb, Bi)-Based Nanomaterials for Cancer Imaging and Therapy: A Materials Perspective
ACS Nano. 2021 Jan 23. doi: 10.1021/acsnano.0c07899.
Yu X, Liu X, Yang K, Chen X, Li W.
870
A hybrid semiconducting organosilica-based O2 nanoeconomizer for on-demand synergistic photothermally boosted radiotherapy
Nat Commun. 2021;12(1):523.
Tang W, Yang Z, He L, Deng L, Fathi P, Zhu S, Li L, Shen B, Wang Z, Jacobson O, Song J, Zou J, Hu P, Wang M, Mu J, Cheng Y, Ma Y, Tang L, Fan W, Chen X
869
177Lu-DOTA-EB-TATE, a Radiolabeled Analogue of Somatostatin Receptor Type 2, for the Imaging and Treatment of Thyroid Cancer
Clin Cancer Res. 2020 Dec 22. doi: 10.1158/1078-0432.CCR-20-3453.
Thakur S, Daley B, Millo C, Cochran C, Jacobson O, Lu H, Wang Z, Kiesewetter D, Chen X, Vasko V, Klubo-Gwiezdzinska J.
868
Stimuli-Responsive Plasmonic Assemblies and Their Biomedical Applications.
Nano Today. 2021;36:101014.
Fu Q, Li Z, Fu F, Chen X, Song J, Yang H.
867
Imaging of Insulinoma by Targeting Glucagonlike Peptide-1 Receptor.
PET Clin. 2021 Feb 12:S1556-8598(20)30103-6.
Luo Y, Chen X